The Löffler Lab

THEME COLOR

MENU POSITION

Publications

2024

Yin, Y., F. Kara-Murdoch, R. W. Murdoch, J. Yan, G. Chen, Y. Xie, Y. Sun and F. E. Löffler (2024). "Nitrous oxide inhibition of methanogenesis represents an underappreciated greenhouse gas emission feedback." Isme j.https://doi.org/10.1093/ismejo/wrae027

2023

Kucharzyk, K. H., Murdoch, F. K., Wilson, J., Michalsen, M., Löffler, F. E., Murdoch, R. W., Istok, J. D., Hatzinger, P. B., Mullins, L., & Hill, A. (2023). Integrated Advanced Molecular Tools Predict In Situ cVOC Degradation Rates: Field Demonstration. Environmental Science & Technology. https://doi.org/10.1021/acs.est.3c06231

Sun, Y., Yin, Y., He, G., Cha, G., Ayala-del-Río, H. L., González, G., Konstantinidis, K. T., & Löffler, F. E. (2023). pH selects for distinct N2O-reducing microbiomes in tropical soil microcosms. bioRxiv, 2023.2011.2029.569236. https://doi.org/10.1101/2023.11.29.569236

Xie, Y., Ramirez, D., Chen, G., He, G., Sun, Y., Murdoch, F. K., & Löffler, F. E. (2023). Genome-Wide Expression Analysis Unravels Fluoroalkane Metabolism in Pseudomonas sp. Strain 273. Environmental Science & Technology, 57(42), 15925-15935. https://doi.org/10.1021/acs.est.3c03855

Xie, Y., Chen, G., Ramirez, D., Yan, J., & Löffler, F. E. Complete (2023). Complete Genome Sequence of Pseudomonas sp. Strain 273, a Haloalkane-Degrading Bacterium. Microbiology Resource Announcements, 0(0), e00176-00123. https://doi.org/doi:10.1128/mra.00176-23

Cui, Y., Li, X., Yan, J., Lv, Y., Jin, H., Wang, J., Chen, G., Kara-Murdoch, F., Yang, Y., & Löffler, F. E. (2023). Dehalogenimonas etheniformans sp. nov., a formate-oxidizing, organohalide-respiring bacterium isolated from grape pomace. International Journal of Systematic and Evolutionary Microbiology, 73(5). https://doi.org/https://doi.org/10.1099/ijsem.0.005881

Song, Y. C., Holland, S. I., Lee, M., Chen, G., Löffler, F. E., Manefield, M. J., Hugenholtz, P., & Kappler, U. (2023). A comparative genome analysis of the Bacillota (Firmicutes) class Dehalobacteriia. Microbial Genomics, 9(6). https://doi.org/10.1099/mgen.0.001039

Zhang, L., Yin, Y., Sun, Y., Liang, X., Graham, D. E., Pierce, E. M., Löffler, F. E., & Gu, B. (2023). Inhibition of Methylmercury and Methane Formation by Nitrous Oxide in Arctic Tundra Soil Microcosms. Environmental Science & Technology, 57(14), 5655-5665. https://doi.org/10.1021/acs.est.2c09457

Vogel, A. L., Thompson, K. J., Straub, D., App, C. B., Gutierrez, T., Löffler, F. E., & Kleindienst, S. (2023). Substrate-independent expression of key functional genes in Cycloclasticus pugetii strain PS-1 limits their use as markers for PAH biodegradation. Front Microbiol, 14, 1185619. https://doi.org/10.3389/fmicb.2023.1185619

Jin, H., Huo, L., Yang, Y., Lv, Y., Wang, J., Maillard, J., Holliger, C., Löffler, F. E., & Yan, J. (2023). Sulfurospirillum diekertiae sp. nov., a tetrachloroethene-respiring bacterium isolated from contaminated soil. Int J Syst Evol Microbiol, 73(2). https://doi.org/10.1099/ijsem.0.005693

Sun, Y., Wang, C., May, A. L., Chen, G., Yin, Y., Xie, Y., Lato, A. M., Im, J., & Löffler, F. E. (2023). Mn(III)-mediated bisphenol a degradation: Mechanisms and products. Water Research, 235, 119787. https://doi.org/https://doi.org/10.1016/j.watres.2023.119787

2022

Zhuang, J., Gill, T., Löffler, F. E., Jin, M., & Sayler, G. S. (2022). Can Food–Energy–Water Nexus Research Keep Pace with Agricultural Innovation? Engineering. https://doi.org/10.1016/j.eng.2022.08.014

Jin, H., Li, X., Wang, H., Cápiro, N. L., Li, X., Löffler, F. E., Yan, J., & Yang, Y. (2022). Anaerobic Biohydrogenation of Isoprene by Acetobacterium wieringae Strain Y. mBio, 13(6), e0208622. https://doi.org/10.1128/mbio.02086-22

Zhuang, J., Löffler, F. E., & Sayler, G. S. (2022). Creating a Research Enterprise Framework for Transdisciplinary Networking to Address the Food–Energy–Water Nexus. Engineering, 11, 95-100. https://doi.org/https://doi.org/10.1016/j.eng.2021.08.017

Chen, G., Kara Murdoch, F., Xie, Y., Murdoch, R. W., Cui, Y., Yang, Y., Yan, J., Key, T. A., & Löffler, F. E. (2022). Dehalogenation of Chlorinated Ethenes to Ethene by a Novel Isolate, "Candidatus Dehalogenimonas etheniformans". Applied Environmental Microbiology, 88(12), e0044322. https://doi.org/10.1128/aem.00443-22

Chen, X., Dai, Y., Zhao, M., Löffler, F. E., & Zhuang, J. (2022). Hydrobiological Mechanism Controlling the Synergistic Effects of Unsaturated Flow and Soil Organic Matter on the Degradation of Emerging Organic Contaminants in Soils. Environmental Science & Technology, 56(16), 11409-11417. https://doi.org/10.1021/acs.est.2c03013

Jiang, L., Yang, Y., Jin, H., Wang, H., Swift, C. M., Xie, Y., Schubert, T., Löffler, F. E., & Yan, J. (2022). Geobacter sp. Strain IAE Dihaloeliminates 1,1,2-Trichloroethane and 1,2-Dichloroethane. Environmental Science & Technology, 56(6), 3430-3440. https://doi.org/10.1021/acs.est.1c05952

Murdoch, R. W., Chen, G., Kara Murdoch, F., Mack, E. E., Villalobos Solis, M. I., Hettich, R. L., & Löffler, F. E. (2022). Identification and widespread environmental distribution of a gene cassette implicated in anaerobic dichloromethane degradation. Global Change Biology, 28(7), 2396-2412. https://doi.org/https://doi.org/10.1111/gcb.16068

May, A. L., Xie, Y., Kara Murdoch, F., Michalsen, M. M., Löffler, F. E., & Campagna, S. R. (2022). Metabolome patterns identify active dechlorination in bioaugmentation consortium SDC-9™. Frontiers in Microbiology, 13. https://doi.org/10.3389/fmicb.2022.981994

Xie, Y., May, A. L., Chen, G., Brown, L. P., Powers, J. B., Tague, E. D., Campagna, S. R., & Löffler, F. E. (2022). Pseudomonas sp. Strain 273 Incorporates Organofluorine into the Lipid Bilayer during Growth with Fluorinated Alkanes. Environmental Science & Technology, 56(12), 8155-8166. https://doi.org/10.1021/acs.est.2c01454

Sexton, D. L., Chen, G., Kara Murdoch, F., Hashimi, A., Löffler, F. E., & Tocheva, E. I. (2022). Ultrastructure of Organohalide-Respiring Dehalococcoidia Revealed by Cryo-Electron Tomography. Applied Environmental Microbiology, 88(2), e0190621. https://doi.org/10.1128/aem.01906-21 2

2021

Sun, Y., Im, J., Shobnam, N., Fanourakis, S. K., He, L., Anovitz, L. M., Erickson, P. R., Sun, H., Zhuang, J., & Löffler, F. E. (2021). Degradation of Adsorbed Bisphenol A by Soluble Mn(III). Environmental Science & Technology, 55(19), 13014-13023. https://doi.org/10.1021/acs.est.1c03862

Podar, M., May, A. L., Bai, W., Peyton, K., Klingeman, D. M., Swift, C. M., Linson, D. A. F., Mathieu, J., Siljeström, D., Beneyto, I., Stadler, L. B., Pinhas, Y., Löffler, F. E., Alvarez, P. J. J., & Kumar, M. (2021). Microbial diversity analysis of two full-scale seawater desalination treatment trains provides insights into detrimental biofilm formation. Journal of Membrane Science Letters, 100001. https://doi.org/10.1016/j.memlet.2021.100001

Zhuang, J., Löffler, F., & Sayler, G. (2021). Closing transdisciplinary collaboration gaps of food-energy-water nexus research. Environmental Science & Policy, 126, 164-167. https://doi.org/https://doi.org/10.1016/j.envsci.2021.10.004

2020

Chen, G., Jiang, N., Villalobos Solis, M. I., Kara Murdoch, F., Murdoch, R. W., Xie, Y., Swift, C. M., Hettich, R. L., & Löffler, F. E. (2021). Anaerobic Microbial Metabolism of Dichloroacetate. mBio, 12(2), e00537-00521. https://doi.org/10.1128/mBio.00537-21

Yang, Y., Yan, J., Li, X., Lv, Y., Cui, Y., Kara-Murdoch, F., Chen, G., & Löffler, F. E. (2020). Genome Sequence of "Candidatus Dehalogenimonas etheniformans" Strain GP, a Vinyl Chloride-Respiring Anaerobe. Microbiology Resource Announcements, 9(50). https://doi.org/10.1128/mra.01212-20

Kucharzyk, K. H., Meisel, J. E., Kara-Murdoch, F., Murdoch, R. W., Higgins, S. A., Vainberg, S., Bartling, C. M., Mullins, L., Hatzinger, P. B., & Löffler, F. E. (2020). Metagenome-Guided Proteomic Quantification of Reductive Dehalogenases in the Dehalococcoides mccartyi-Containing Consortium SDC-9. Journal of Proteome Research, 19(4), 1812-1823. https://doi.org/10.1021/acs.jproteome.0c00072

Chen, G., Fisch, A. R., Gibson, C. M., Erin Mack, E., Seger, E. S., Campagna, S. R., & Löffler, F. E. (2020). Mineralization versus fermentation: evidence for two distinct anaerobic bacterial degradation pathways for dichloromethane. The ISME Journal, 14(4), 959-970. https://doi.org/10.1038/s41396-019-0579-5

2019

Kaya, D., B.V. Kjellerup, K. Chourey, R.L. Hettich, D.M. Taggart, F.E. Löffler. 2019. Impact of fixed nitrogen availability on Dehalococcoides mccartyi reductive dechlorination activity. Environ. Sci. Technol. In Press. | doi: 10.1021/acs.est.9b04463.

Im, J., E.E. Mack, E.S. Seger, and F.E. Löffler. 2019. Biotic and abiotic degradation of 1,1,2-trichloro-1,2,2-trifluoroethane (CFC-113): Implications for bacterial detoxification of chlorinated ethenes. Environ. Sci. Technol. 53:11941-11948. | doi: 10.1021/acs.est.9b04399.

Manoharan, L., J.A. Kozlowski, R.W. Murdoch, F.E. Löffler, F.L. Sousa, and C. Schleper. 2019. Metagenomes from coastal marine sediments give insights into the ecological role and cellular features of Loki- and Thorarchaeota. mBio 10:e02039-19. | doi.org/10.1128/ mBio.02039-19.

Orellana, L.H., J.K. Hatt, R. Iyer, K. Chourey, R.L. Hettich, J.C. Spain, W.H. Yang, J.C. Chee-Sanford, R.A. Sanford, F.E. Löffler, and K.T. Konstantinidis. 2019. Comparing DNA, RNA and protein levels for measuring microbial activity in nitrogen-amended soils. Scientific Reports. 9: 17630 (2019) 9:17630 | https://doi.org/10.1038/s41598-019-53679-0.

Lawson, C.E., W.R. Harcombe, R. Hatzenpichler, S.R. Lindemann, F.E. Löffler, M.A. O’Malley, H. García-Martin, B.F. Pfleger, L. Raskin, O.S. Venturelli, D.G. Weissbrodt, D.R. Noguera, and K.D. McMahon. 2019. Unmasking common principles and practices for microbiome engineering. Nature Microbiology, 17:725-741. | doi: 10.1038/s41579-019-0255-9.

Yan, J., Y. Yang, X. Li, and F.E. Löffler. 2019. Complete genome sequence of Dehalococcoides mccartyi strain FL2, a trichloroethene-respiring anaerobe isolated from pristine freshwater sediment. Microbiology Resource Announcements. 8:e00558-19. | doi.org/ 10.1128/MRA.00558-19.

Villalobos Solis, M.I., P.E. Abraham, K. Chourey, CM Swift, F.E. Löffler, and R.L. Hettich. 2019. Targeted detection of Dehalococcoides mccartyi microbial protein biomarkers as indicators of reductive dechlorination activity in contaminated groundwater. Scientific Reports, 9:10604 | doi.org/10.1038/s41598-019-46901-6.

Chen, H., Z.K. Yang, D. Yip, R.H. Morris, S.J. Lebreux, M.A. Cregger, D.M. Klingeman, D. Hui, R.L. Hettich, S.W. Wilhelm, G. Wang, F.E. Löffler, and C.W. Schadt. 2019. One-time nitrogen fertilization shifts switchgrass soil microbiomes within a context of larger spatial and temporal variation. PLoS ONE 14(6): e0211310. https://doi.org/10.1371/journal.pone.0211310.

Liang X., J. Zhuang, F.E. Löffler, Y. Zhang, J. DeBruyn, S. Wilhelm, S.M. Schaeffer, and M. Radosevich. 2019. Viral and bacterial community responses to stimulated Fe(III)-bioreduction during simulated subsurface bioremediation. Environ. Microbiol. 6:2043-2055 | doi:10.1111/1462-2920.14566.

Yin, Y., Yan, G. Chen, F. Kara Murdoch, N. Pfisterer, and F.E. Löffler. 2019. Nitrous oxide is a potent inhibitor of bacterial reductive dechlorination. Environ. Sci. Technol. 53:692-701. | doi: 10.1021/acs.est.8b05871.

Kleindienst, S., K. Chourey, G. Chen, R. Iyer, R.L. Hettich, S.R. Campagna, E.E. Mack, E.S. Seger, and F.E. Löffler. 2019. Proteogenomics reveals novel reductive dehalogenases and methyltransferases expressed during anaerobic dichloromethane metabolism. Appl. Environ. Microbiol. 85:e02768-18 | doi: 10.1128/AEM.02768-18.

Liang X., M. Radosevich, F.E. Löffler, S.M. Schaeffer, and J. Zhuang. 2019. Impact of microbial iron oxide reduction on the transport of diffusible tracers and non-diffusible nanoparticles in soils. Chemosphere, 220:391-402. | doi.org/10.1016/j.chemosphere.2018.12.165.

2018

Higgins, S.A., E. Padilla-Crespo, and F.E. Löffler. 2018. Draft genome sequences of the 1,2-dichloropropane-respiring Dehalococcoides mccartyi strains RC and KS. Microbiol. Resour. Announc. 7:e01081-18. | doi.org/10.1128/ MRA.01081-18.

Clark, K., D.M. Taggart, B.R. Baldwin, K.M. Ritalahti, R.W. Murdoch, J.K. Hatt, and F.E. Löffler. 2018. Normalized quantitative PCR measurements as predictors for ethene formation at sites impacted with chlorinated ethenes. Environ. Sci. Technol. 52:13410-13420. | doi: 10.1021/acs.est.8b04373.

Higgins, S.A., C.W. Schadt, P.B. Matheny, and F.E. Löffler. 2018. Phylogenomics reveals dynamic evolution of fungal p450nor and its undiscovered relationship to secondary metabolism. Genome Biol. Evol. 10:2474-2489. | doi: 10.1093/gbe/evy187.

Marcet, T., N. Capiro, Y. Yang, F.E. Löffler, and K.D. Pennell. 2018. Impacts of low-temperature thermal treatment on microbial detoxification of tetrachloroethene under continuous flow conditions. Water Research, 145:21-29. | doi.org/10.1016/j.watres.2018.07.076.

Marcet, T., N. Capiro, L.A. Morris, S.M. Hassan, Y. Yang, F.E. Löffler, and K.D. Pennell. 2018. Release of electron donors during thermal treatment of soils. Environ. Sci. Technol. 52:3642-3651. | doi.org/10.1021/acs.est.7b06014.

Chen, G., O. Shouakar-Stash, E. Phillips, S.D. Justicia-Leon, T. Gilevska, B. Sherwood Lollar, E.E. Mack, E.S. Seger, and F.E. Löffler. 2018. Dual carbon-chlorine isotope analysis indicates distinct anaerobic dichloromethane degradation pathways in two members of the Peptococcaceae . Environ. Sci. Technol., 52:8607-8616. | doi: 10.1021/acs.est.8b01583.

Hallin, S., L. Philippot, F.E. Löffler, R.A. Sanford, and C.M. Jones. 2018. Genomics and ecology of novel N₂ O reducing microorganisms. Trends Microbiol. 26:43-55. | doi: 10.1016/j.tim.2017.07.003.

Onley, J.R., S. Ahsan, R.A. Sanford, and F.E. Löffler. 2018. Denitrification by Anaeromyxobacter dehalogenans , a common soil bacterium lacking the nitrite reductase genes nirS and nirK . Appl. Environ. Microbiol. 84:e01985-17. | doi.org/10.1128/AEM.01985-17.

Orellana, L.H., J.C. Chee-Sanford, R.A. Sanford, F.E. Löffler, and K.T. Konstantinidis. 2018. Year-round shotgun metagenomes reveal stable microbial communities in agricultural soils and novel ammonia oxidizers responding to fertilization. Appl. Environ. Microbiol. 84:e01646-17. | doi: 10.1128/AEM.01646-17.

Yan, J., M. Bi, A.K. Bourdon, A.T. Farmer, P.-H. Wang, O. Molenda, A. Quaile, N. Jiang, Y. Yang, Y. Yin, B. Şimşir, S.R. Campagna, E.A. Edwards, and F.E. Löffler. 2018. Purinyl-cobamide is a native prosthetic group of reductive dehalogenases. Nat. Chem. Biol. 14:8-14. | doi:10.1038/nchembio.2512.

2017

Yang, Y., N.L. Cápiro, J. Yan, T.F. Marcet, K.D. Pennell, and F.E. Löffler. 2017. Resilience and recovery of Dehalococcoides mccartyi following low pH exposure. FEMS Microbiol. Ecol. 93(12). | doi: 10.1093/femsec/fix130.

Chen, G., S. Kleindienst, D.R. Griffiths, E.E. Mack, E.S. Seger, and F.E. Löffler. 2017. Mutualistic interaction between dichloromethane- and chloromethane-degrading populations in an anaerobic consortium. Environ. Microbiol. 19:4784-4796. | doi: 10.1111/1462-2920.13945.

Chen, G., R. Murdoch, E.E. Mack, E.S. Seger, and F.E. Löffler. 2017. Complete genome sequence of Dehalobacter ium formicoaceticum , a strictly anaerobic dichloromethane-degrading bacterium. Genome Announc. 5:37 e00897-17. | doi: 10.1128/genomeA.00897-17.

Yang, Y., N.L. Cápiro, T.F. Marcet, J. Yan, K.D. Pennell, and F.E. Löffler. 2017. Organohalide respiration with chlorinated ethenes under low pH conditions. Environ. Sci. Technol. 51:8579-8588. | doi: 10.1021/acs.est.7b01510.

Yang, Y., S.A. Higgins, J. Yan, B. Şimşir, K. Chourey, R. Iyer, R.L. Hettich, B. Baldwin, D.M. Ogles, and F.E. Löffler. 2017. Grape pomace compost harbors organohalide-respiring Dehalogenimonas species with novel reductive dehalogenase genes. The ISME Journal. 11:2767-2780. | doi: 10.1038/ismej.2017.127.

Chowdhary, J., F.E. Löffler, and J.C. Smith. 2017. Community detection in sequence similarity networks based on attribute clustering. PLoS ONE. 12(7):e0178650. | doi: 10.1371/journal.pone.0178650.

Şimşir, B., J. Yan, J. Im, D. Graves, and F. E. Löffler. 2017. Natural attenuation in streambed sediment receiving chlorinated solvents from underlying fracture networks. Environ. Sci. Technol. 51:4821-4830. | doi: 10.1021/acs.est.6b05554.

Kleindienst, S. S.A. Higgins, D. Tsementzi, G. Chen, K.T. Konstantinidis, E.E. Mack, F. E. Löffler. 2017. ‘Candidatus Dichloromethanomonas elyunquensis’ gen. nov., sp. nov., a dichloromethane-degrading anaerobe of the Peptococcaceae family. Syst. Appl. Microbiol. 40:150-159. | doi: 10.1016/j.syapm.2016.12.001.

Wang, P. H., S. Tang, K. Nemr, R. Flick, J. Yan, R. Mahadevan, A. Yakunin, and F. E. Löffler, and E. A. Edwards. 2017. Refined experimental annotation reveals conserved corrinoid autotrophy in chloroform-respiring Dehalobacter isolates. ISME J. 11:626-640. | doi:10.1038/ismej.2016.158.

2016

Im, J., and F.E. Löffler. 2016. Fate of Bisphenol A in terrestrial and aquatic environments. Environ. Sci. Technol. 50:8403-8416. | doi: 10.1021/acs.est.6b00877.

Adrian, L. and F.E. Löffler (Eds). Organohalide-Respiring Bacteria. 2016. Springer-Verlag, Berlin Heidelberg. ISBN 978-3-662-49873-6. | doi: 10.1007/978-3-662-49875-0 http://link.springer.com/book/10.1007/978-3-662-49875-0.

Sanford, R.A., J. Chowdhary, and F.E. Löffler. Organohalide-respiring Deltaproteobacteria. In A Adrian, L. and F.E. Löffler (Eds). Organohalide Respiring Bacteria. 2016. Springer-Verlag, Berlin Heidelberg. ISBN 978-3-662-49873-6. | doi: 10.1007/978-3-662-49875-0.

Adrian, L. and F.E. Löffler. 2016. Organohalide-respiring bacteria - an introduction. In A Adrian, L. and F.E. Löffler (Eds). Organohalide Respiring Bacteria. 2016. Springer-Verlag, Berlin Heidelberg. ISBN 978-3-662-49873-6. | doi: 10.1007/978-3-662-49875-0.

Adrian, L. and F.E. Löffler. 2016. Outlook - The next frontiers for research on organohalide-respiring bacteria. In A Adrian, L. and F.E. Löffler (Eds). Organohalide Respiring Bacteria. 2016. Springer-Verlag, Berlin Heidelberg. ISBN 978-3-662-49873-6. | doi: 10.1007/978-3-662-49875-0.

Im, J., D. Yip, J. Lee, F.E. Löffler. 2016. Simplified extraction of bisphenols from bacterial culture suspensions and solid matrices. J. Microbiol. Methods. 126:35-37. | doi: 10.1016/j.mimet.2016.05.005.

Lee, J., J. Im, U. Kim, and F. E. Löffler. 2016. A data mining approach to predict in situ detoxification potential of chlorinated ethenes. Environ. Sci. Technol. 50:5181-5188. | doi: 10.1021/acs.est.5b05090.

Yoon, S., S. Nissen, D. Park, R.A. Sanford, and F.E. Löffler. 2016. Nitrous oxide reduction kinetics distinguish bacteria harboring clade I nosZ from those harboring clade II nosZ. Appl. Environ. Microbiol. 82:3793-3800. | doi: 10.1128/AEM.00409-16.

Higgins, S.A., A. Welsh, L.H. Orellana, K.T. Konstantinidis, J. Chee-Sanford, R.A. Sanford, C.W. Schadt, and F.E. Löffler. 2016. Detection and diversity of fungal cytochrome nitric oxide reductase genes (p450nor ) in agricultural soils. Appl. Environ. Microbiol. 82:2919-2928. | doi: 10.1128/AEM.00243-16.

Tang, S., Wang, P. H., S. A. Higgins, F. E. Löffler, and E. A. Edwards. 2016. Sister Dehalobacter genomes reveal specialization in organohalide respiration and recent strain differentiation likely driven by chlorinated substrates. Front. Microbiol. 7:100 | doi: 10.3389/fmicb.2016.00100.

Kleindienst, S., S.A. Higgins, D. Tsementzi, K.T. Konstantinidis, E.E. Mack, and F.E. Löffler. 2016. Draft genome of a strictly anaerobic dichloromethane-degrading bacterium. Genome Announcements. 4:2 e00037-16. | doi: 10.1128/genomeA.00037-16.

Yan, J., B. Şimşir, A.T. Farmer, M. Bi, Y. Yang, S.R. Campagna, and F.E. Löffler. 2016. The corrinoid cofactor of reductive dehalogenases affects dechlorination rates and extents in organohalide-respiring Dehalococcoides mccartyi . ISME J. 10:1092-1101. | doi: 10.1038/ismej.2015.197. 82:2919-2928. | doi: 10.1128/AEM.00243-16.

2015

Cápiro, N. L., F. E. Löffler, and K. D. Pennell. 2015. Spatial and temporal dynamics of organohalide-respiring bacteria in a heterogeneous PCE-DNAPL source zone. J. Contam. Hydrol. 182:78-90. | doi: 10.1021/es501320h.

Im, I., G. Walshe-Langford, J.-W. Moon, and F. E. Löffler. 2015. Response to comment on environmental fate of the next generation refrigerant 2,3,3,3-tetrafluoropropene (HFO-1234yf). Environ. Sci. Technol. 49:8265-8266. | doi: 10.1021/acs.est.5b01970.

Im, I., C. W. Prevatte, S. R. Campagna, and F. E. Löffler. 2015. Identification of 4-hydroxycumyl alcohol as the major MnO₂ -mediated bisphenol A transformation product and evaluation of its environmental fate. Environ. Sci. Technol. 49: 6214-6221. doi: 10.1021/acs.est.5b00372.

Yoon, S., R. A. Sanford, and F. E. Löffler. 2015. Nitrite control over dissimilatory nitrate/nitrite reduction pathways in Shewanella loihica strain PV-4. Appl. Environ. Microbiol. 81:3510-3517. | doi: 10.1128/AEM.00688-15.

Hwang, C., A. Copeland, S. Lucas, A. Lapidus, K. Barry, T. Glavina del Rio, E. Dalin, H. Tice, S. Pitluck, D. Sims, T. Brettin, D.C. Bruce, J.C. Detter, C.S. Han, J. Schmutz, F.W. Larimer, M.L. Land, L.J. Hauser, N. Kyrpides, A. Lykidis, P. Richardson, A Belieav, R.A. Sanford, F.E. Löffler, and M.W. Fields. 2015. Complete genome sequence of Anaeromyxobacter sp. Fw109-5, an anaerobic, metal-reducing bacterium isolated from contaminated subsurface environment. Genome Announcements. 3:e01449-14. | doi: 10.1128/genomeA.01449-14.

Yoon, S., C. Cruz-García, R. Sanford, K. M. Ritalahti, and F. E. Löffler. 2015. Denitrification versus ammonification: environmental controls of two competing respiratory nitrate/nitrite reduction pathways in Shewanella loihica . ISME J. 9:1093-1104. | doi: 10.1038/ismej.2014.201.

2014

Miyazaki, M., S. Sakai, K. M. Ritalahti, Y. Saito, Y. Yamanaka, Y. Saito, A. Tame, K. Uematsu, F. E. Löffler, K. Takai, and H. Imachi. 2014. Sphaerochaeta multiformis sp. nov., an anaerobic, psychrophlic bacterium isolated from subseafloor sediment offshore Shimokita, Japan, and emended description of the genus Sphaerochaeta . IJSEM, 64:4147-4154. | doi: 10.1099/ijs.0.068148-0.

Im, I., G. Walshe-Langford, J.-W. Moon, and F. E. Löffler. 2014. Environmental fate of the next generation refrigerant 2,3,3,3-tetrafluoropropene (HFO-1234yf). Environ. Sci. Technol. 48:13181-13187. doi: 10.1021/es5032147.

Im, I., C. W. Prevatte, H. G. Lee, S. R. Campagna, and F. E. Löffler. 2014. 4-Methylphenol produced in freshwater sediment microcosms is not a bisphenol A metabolite. Chemosphere, 117:521-526. | doi: 10.1016/j.chemosphere.2014.09.008.

Cápiro, N. L., Y. Wang, J. K. Hatt, C. A. Lebrón, K. D. Pennell, and F. E. Löffler. 2014. Distribution of organohalide-respiring bacteria between solid and aqueous phase. Environ. Sci. Technol. 48:10878-10887. | doi: 10.1021/es501320h. .

Cretnik, S., A. Bernstein, O. Shouakar-Stash, F. E. Löffler, and M. Elsner. 2014. Chlorine isotope effects from isotope ratio mass spectrometry suggest intramolecular C-Cl bond competition in trichloroethene (TCE) reductive dehalogenation. Molecules. 19: 6450-6473. | doi:10.3390/molecules19056450.

Orellana, L. H., L. M. Rodriguez-R, S. A. Higgins, J. C. Chee-Sanford, R. A. Sanford, K. M. Ritalahti, F. E. Löffler, and K. T. Konstantinidis. 2014. Detecting nitrous oxide reductase (nosZ ) genes in soil metagenomes: method development and implications for the nitrogen cycle. mBio 5:3 e01193-14. | doi: 10.1128/mBio.01193-14.

Basu, A., R. A. Sanford, T. M. Johnson, C. C. Lundstrom, and F. E. Löffler. 2014. Uranium isotopic fractionation factors during U(VI) reduction by bacterial isolates. Geochim. Cosmochim. Acta. 136:100-113. | doi: 10.1016/j.gca.2014.02.041.

Welsh, A. J. C. Chee-Sanford, L. Connor, F. E. Löffler, and R. A. Sanford. 2014. Refined NrfA phylogeny improves PCR-based nrfA gene detection. Appl. Environ. Microbiol. 80:2110-2119. | doi: 10.1128/AEM.03443-13.

Justicia-Leon, S. D., S. Higgins, E. Erin Mack, D. R. Griffiths, S. Tang, E. A. Edwards, and F. E. Löffler. 2014. Bioaugmentation with distinct Dehalobacter strains achieves chloroform detoxification in microcosms. Environ. Sci. Technol. 48:1851-1858. | doi: 10.1021/es403582f.

Sha, K., S.-H. Choia, J. Im, G. Geni Lee, F. E. Löffler, and J. H. Park. 2014. Regulation of ethanol-related behavior and ethanol metabolism by the Corazonin neurons and Corazonin receptor in Drosophila melanogaster . PLoS ONE. 9: e87062. | doi: 10.1371/journal.pone.0087062.

Padilla-Crespo, E., J. Yan, C. Swift, D. D. Wagner, K. Chourey, R. L. Hettich, K. M. Ritalahti, and F. E. Löffler. 2014. Identification and environmental distribution of dcpA encoding a 1,2-dichloropropane-to-propene reductive dehalogenase in Dehalococcoides mccartyi . Appl. Environ. Microbiol. 80:808-818. | doi: 10.1128/AEM.02927-13.

2013

Löffler, F. E., K. M. Ritalahti and S. H. Zinder. 2013. Dehalococcoides and reductive dechlorination. SERDP ESTCP Environmental Remediation Technology, Vol. 5. H. F. Stroo, A. Leeson, and H. C. Ward (Eds.). Bioaugmentation for Groundwater Remediation. Springer, New York. ISBN 978-1-4614-4114-4. | doi: 110.1007/978-1-4614-4115-1

Im, I., J. Lee, and F. E. Löffler. 2013. Interference of ferric ions with ferrous ion quantification using the ferrozine assay. J. Microbiol. Methods. 95:366-367. doi: 10.1016/j.mimet.2013.10.005.

Chourey, K., S. Nissen, T. Vishnivetskaya, M. Shah, S. Pfiffner, R. L. Hettich, and F. E. Löffler. 2013. Environmental proteomics reveals early microbial community responses to biostimulation at a uranium- and nitrate-contaminated site. Proteomics. 13:2921-2930. | doi: 10.1002/pmic.201300155.

Hatt, J. K., K. M. Ritalahti, D. M. Ogles, C. A. Lebrón, and F. E. Löffler. 2013. Design and application of an internal amplification control (IAC) to improve Dehalococcoides mccartyi 16S rRNA gene enumeration by qPCR. Environ. Sci. Technol. 47: 11131-11138. | doi: 10.1021/es4019817.

Chen, M., L. M. Abriola, B. K. Amos, E. J. Suchomel, K. D. Pennell, F. E. Löffler, and J. A. Christ. 2013. Microbially enhanced dissolution and reductive dechlorination of PCE by a mixed culture: model validation and sensitivity analysis. J. Contam. Hydrol. 151:117-130. | doi: 10.1016/j.jconhyd.2013.05.005.

Yan, J., J. Im, Y. Yi, and F. E. Löffler. 2013. Guided cobalamin biosynthesis supports Dehalococcoides mccartyi reductive dechlorination activity. Phil. Trans. R. Soc. B. 368, 20120320. | doi: 10.1098/rstb.2012.0320.

Hug, L. A., F. Maphosa, D. Leys, Frank E. Löffler, H. Smidt, E. A. Edwards, and L. Adrian. 2013. Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases. Phil. Trans. R. Soc. B 368, 20120322. | doi: 10.1098/rstb.2012.0322.

Yoon, S. R. A. Sanford, and F. E. Löffler. 2013. Shewanella spp. use acetate as electron donor for denitrification but not ferric iron or fumarate reduction. Appl. Environ. Microbiol. 79: 2818-2822. | doi: 10.1128/AEM.03872-12.

Löffler, F. E., J. Yan, K. M. Ritalahti, L. Adrian, E. A. Edwards, K. T. Konstantinidis, J. A. Müller, H. Fullerton, S. Zinder, and A. M. Spormann. 2013. Dehalococcoides mccartyi gen. nov., sp. nov., obligately organohalide-respiring anaerobic bacteria relevant to halogen cycling and bioremediation, belong to a novel bacterial class, Dehalococcoidia classis nov., order Dehalococcoidales ord. nov. and family Dehalococcoidaceae fam. nov., within the phylum Chloroflexi . Int. J. Syst. Evol. Microbiol. 63:625-635. | doi: 10.1099/ijs.0.034926-0.

Tang, S., W. W. M. Chan, K. E. Fletcher, J. Seifert, X. Liang, F. E. Löffler, E. A. Edwards, and L. Adrian. 2013. Functional characterization of reductive dehalogenases using blue native polyacrylamide gel electrophoresis. Appl. Environ. Microbiol. 79:974-981. | doi: 10.1128/AEM.01873-12.

2012

Sanford, R. A., D. D. Wagner, Q. Wu, J. C. Chee-Sanford, S. H. Thomas, C. Cruz-García, G. Rodríguez, A. Massol-Deyá, K. K. Krishnani, K. M. Ritalahti, S. Nissen, K. T. Konstantinidis, and F. E. Löffler. 2012. Unexpected non-denitrifier nitrous oxide reductase gene diversity and abundance in soils. Proc. Natl. Acad. Sci. USA. 109:19709-19714. | doi: 10.1073/pnas.1211238109.

Nissen, S., X. Liu, K. Chourey, R. L. Hettich, D. D. Wagner, S. M. Pfiffner, and F. E. Löffler. 2012. Comparative c-type expression analysis in Shewanella oneidensis strain MR-1 and Anaeromyxobacter dehalogenans strain 2CP-C grown with soluble and insoluble oxidized metal electron acceptors. Biochem. Soc. Trans. 40:1204-1210. | doi: 10.1042/BST20120182.

Yan, J., K. M. Ritalahti, D. D. Wagner, and F. E. Löffler. 2012. Unexpected specificity of interspecies cobamide transfer from Geobacter spp. to organohalide-respiring Dehalococcoides mccartyi strains. Appl. Environ. Microbiol. 78:6630-6636. doi: 10.1128/AEM.01535-12.

Caro-Quintero, A., K. M. Ritalahti, K. D. Cusick, F. E. Löffler, and K. T. Konstantinidis. 2012. The chimeric genome of Sphaerochaeta : non-spiral spirochetes that break with the prevalent dogma in spirochete biology. mBio 3:3 e00025-12. | doi:10.1128/mBio.00025-12.

Wagner, D. D., L. A. Hug, J. K. Hatt, M. R. Spitzmiller, E. Padilla-Crespo, K. M. Ritalahti, E. A. Edwards, K. T. Konstantinidis, and F. E. Löffler. 2012. Genomic determinants of organohalide-respiration in Geobacter lovleyi , an unusual member of the Geobacteraceae . BMC Genomics, 13:200-216. | doi:10.1186/1471-2164-13-200.

Ritalahti, K. M, S. D. Justicia Leon, K. D. Cusick, N. Ramos-Hernandez, M. Rubin, J. Dornbush, and F. E. Löffler. 2012. Isolation of Sphaerochaeta (gen. nov.), free-living, spherical spirochetes, and characterization of Sphaerochaeta pleomorpha (sp. nov.) and Sphaerochaeta globosa (sp. nov.). IJSEM. 62:210-216. | doi: 10.1099/ijs.0.023986-0.

Justicia-Leon, S., K. M. Ritalahti, E. E. Mack, and F. E. Löffler. 2012. Dichloromethane fermentation by a Dehalobacter sp. in an enrichment culture derived from pristine river sediment. Appl. Environ. Microbiol. 78:1288-1291. | doi: 10.1128/AEM.07325-11.

Hatt, J. K., and F. E. Löffler. 2012. Quantitative real-time PCR (qPCR) detection chemistries affect enumeration of the Dehalococcoides 16S rRNA gene in groundwater. J. Microbiol. Methods. 88:263-270. doi: 10.1016/j.mimet.2011.12.005.

2011

Chan, W. W.M., A. Grostern, F. E. Löffler, and E A. Edwards. 2011. Quantifying the effects of 1,1,1-trichloroethane and 1,1-dichloroethane on chlorinated ethene reductive dehalogenases. Environ. Sci. Technol. 45:9693-9702. doi: 10.1021/es201260n.

Fletcher, K. E., J. Costanza, K. P. Pennell, and F. E. Löffler. 2011. Electron donor availability for microbial reductive processes following thermal treatment. Water Research. 45:6625-6636. doi: 10.1016/j.watres.2011.09.033.

Ford T.E., A.L. Bass, S. Cheng, G.N. Cherr, B. Cole, E. Fairbairn, J.D. Gu, R.S. Halbrook, F.E. Löffler, E.L. Madsen, and N.A. McGinn. 2011. EHPC 2010: sharing knowledge on environmental health for risk mitigation. Ecotoxicology. 20:937-939. | doi: 10.1007/s10646-011-0656-7.

Boyanov, M. I., K. E. Fletcher, M. Jae Kwon, X. Rui, E. J. O’Loughlin, F. E. Löffler, and K. M. Kemner. 2011. Solution and microbial controls on the formation of reduced U(IV) species. Environ. Sci. Technol. 45:8336-8344. | doi: 10.1021/es2014049.

Fletcher, K. E., I. Nijenhuis, H.-H. Richnow, and F. E. Löffler. 2011. Stable carbon isotope enrichment factors for cis-1,2-dichloroethene and vinyl chloride reductive dechlorination by Dehalococcoides . Environ. Sci. Technol. 45: 2951-2957. | doi: 10.1021/es103728q.

Cruz-García, C., A. E. Murray, J. L.M. Rodrigues, J. A. Gralnick, L. A. McCue, M. F. Romine, F. E. Löffler, and J. M. Tiedje. 2011. Fnr (EtrA) acts as a fine-tuning regulator of anaerobic metabolism in Shewanella oneidensis MR-1. BMC Microbiology. 11:64. | doi:10.1186/1471-2180-11-64.

Fletcher, K. E., C. Cruz-Garcia, N. S. Ramaswamy, J. Costanza, K. D. Pennell, and F. E. Löffler. 2011. Effects of elevated temperatures on Dehalococcoides dechlorination performance and biomarker gene and transcript quantification. Environ. Sci. Technol. 45:712-718. | doi: 10.1021/es1023477.

Cápiro, N. L., E. K. Granbery, C. A. Lebrón, D. W. Major, M. L. McMaster, M. J. Pound, F. E. Löffler and K. D. Pennell. 2011. Liquid-liquid mass transfer of partitioning electron donors in chlorinated solvent source zones. Environ. Sci. Technol. 45: 1547-1554. | doi: 10.1021/es102249x.

Lee, J., T. K. Lee, F. E. Löffler and J. Park. 2011. Characterization of microbial community structure and population dynamics of tetrachloroethene-dechlorinating tidal mudflat communities. Biodegradation. 22:687-698. | doi: 10.1007/s10532-010-9429-x.

Lee N. M., D. B. Meisinger, M. Schmid, M. Rothballer, and F. E. Löffler. 2011. Fluorescence In Situ Hybridization (FISH). In: Encyclopedia of Earth Sciences Series, Encyclopedia of Geobiology, Part 6 (eds. J. Reitner, V. Thiel). Heidelberg, Germany: Springer Verlag, pp. 373-393. | doi: 10.1007/978-1-4020-9212-1_91.

2010

Ritalahti, K. M., J. K. Hatt, V. Lugmayr, K. Henn, E. Petrovskis, D. M. Ogles, G. A. Davis, C. M. Yeager, C. A. Lebrón, and F. E. Löffler. 2010. Comparing on-site to off-site biomass collection for Dehalococcoides biomarker gene quantification to predict in situ chlorinated ethene detoxification potential. Environ. Sci. Technol. 44:5127-5133. | doi: 10.1021/es100408r.

Wu, W., J. Carley, S. J. Green, J. Luo, S. D. Kelly, J. van Nostrand, K. Lowe, T. Mehlhorn, S. Carroll, B. Boonchayanant, F. E. Löffler, D. Watson, K. M. Kemner, J. Zhuo, P. K. Kitanidis, J. E. Kostka, P. M. Jardine, and C. S. Criddle. 2010. Effects of nitrate on the stability of uranium in a bioreduced region of the subsurface. Environ. Sci. Technol. 44:5104-5111. | doi: 10.1021/es1000837.

Fletcher, K. E., M. I. Boyanov, S. H. Thomas, Q. Wu, K. M. Kemner, and F. E. Löffler. 2010. Uranium reduction to mononuclear U(IV) by Desulfitobacterium spp. Environ. Sci. Technol. 44:4705-4709. doi: 10.1021/es903636c.

Thomas, S. H., R. A. Sanford, M. B. Leigh, E. Cardenas, and F. E. Löffler. 2010. Unique ecophysiology among U(VI)-reducing bacteria as revealed by evaluation of oxygen metabolism in Anaeromyxobacter dehalogenans strain 2CP-C. Appl. Environ. Microbiol. 76:176-183. | doi: 10.1128/AEM.01854-09.

Ritalahti, K. M., C. Cruz-García, E. Padilla-Crespo, J. K. Hatt, and F. E. Löffler. 2010. RNA extraction and cDNA analysis for quantitative assessment of biomarker transcripts in groundwater. In K. N. Timmis (ed.), Handbook of Hydrocarbon and Lipid Microbiology. Springer Berlin Heidelberg, Part 32, pages 3671-3685. | doi: 10.1007/978-3-540-77587-4_289.

Ritalahti, K. M., J. K. Hatt, E. Petrovskis, and F. E. Löffler. 2010. Groundwater sampling for nucleic acid biomarker analysis. In K. N. Timmis (ed.), Handbook of Hydrocarbon and Lipid Microbiology. Springer Berlin Heidelberg, Part 31, pages 3407-3418. | doi: 10.1007/978-3-540-77587-4_265.

2009

McMurdie, P. J., S. F. Behrens, J. A. Müller, J. Göke, K. M. Ritalahti, R. D. Wagner, S. Holmes, P. Richardson, F. E. Löffler, and A. M. Spormann. 2009. Localized plasticity in the streamlined genomes of vinyl chloride respiring Dehalococcoides . PLoS Genet 5(11): e1000714. | doi:10.1371/journal.pgen.1000714.

Fletcher, K. E., F. E. Löffler, H.-H. Richnow, and I. Nijenhuis. 2009. Stable carbon isotope fractionation of 1,2-dichloropropane during dichloroelimination by Dehalococcoides populations. Environ. Sci. Technol. 43:6915-6919. | doi: 10.1021/es900365x.

Pavlekovic, M., M. C. Schmid, N., Schmider-Poignee, C. Spring, M. Pilhofer, T. Gaul, M. Fiandaca, F. E. Löffler, M. Jetten, K.-H. Schleifer, and N. M. Lee. 2009. Optimization of three FISH procedures for in situ detection of anaerobic ammonium oxidizing bacteria in biological wastewater treatment. J. Microbial. Meth. 78:119-126. | doi: 10.1016/j.mimet.2009.04.003.

Thomas, S. H., E. Padilla-Crespo, P. M. Jardine, R. A. Sanford, F. E. Löffler. 2009. Diversity and distribution of Anaeromyxobacter strains in a U(VI)-contaminated subsurface environment with nonuniform flow. Appl. Environ. Microbiol. 75:3679-3687. doi: 10.1128/AEM.02473-08.

Amos, B. K., E. J. Suchomel, K. D. Pennell, and F. E. Löffler. 2009. Spatial and temporal distributions of Geobacter lovleyi and Dehalococcoides spp. during bioenhanced PCE-NAPL dissolution. Environ. Sci. Technol. 43:1977-1985. | doi: 10.1021/es8027692.

Costanza, J., K. E. Fletcher, F. E. Löffler, and K. D. Pennell. 2009. Fate of TCE in heated Fort Lewis soil. Environ. Sci. Technol. 43:909-914. | doi: 10.1021/es802508x.

Himmelheber, D. W., S. H. Thomas, F. E. Löffler, M. Taillefert, and J. B. Hughes. 2009. Microbial colonization of an in situ sediment cap and correlation to stratified redox zones. Environ. Sci. Technol. 43:66-74. | doi: 10.1021/es801834e.

Marshall, M. J., A. C. Dohnalkova, D. W. Kennedy, A. E. Plymale, S. H. Thomas, F. E. Löffler, R. A. Sanford, J. M. Zachara, J. K. Fredrickson, and A. S. Beliaev. 2009. Electron donor-dependent radionuclide reduction and nanoparticle formation by Anaeromyxobacter dehalogenans strain 2CP-C. Environ. Microbiol. 11:534-543. doi: 10.1111/j.1462-2920.2008.01795.x.

2008

Strycharz, S. M., T. L. Woodard, J. P. Johnson, K. P. Nevin, R. A. Sanford, F. E. Löffler, and D. R. Lovley. 2008. Graphite electrode as a sole electron donor for reductive dechlorination of tetrachlorethene by Geobacter lovleyi . Appl. Environ. Microbiol. 74:5943-5947. | doi: 10.1128/AEM.00961-08.

Fletcher, K. E., K. M. Ritalahti, K. D. Pennell, K. Takamizawa, and F. E. Löffler. 2008. Resolution of culture Clostridium bifermentans DPH-1 into two populations: A Clostridium sp. and tetrachloroethene (PCE) dechlorinating Desulfitobacterium hafniense strain JH1. Appl. Environ. Microbiol. 74: 6141-6143. | doi: 10.1128/AEM.00994-08.

Amos, B. A., K. M. Ritalahti, C. Cruz-Garcia, E. Padilla-Crespo, and F. E. Löffler. 2008. Oxygen effect on Dehalococcoides viability and biomarker quantification. Environ. Sci. Technol. 42:5718-5726. | doi: 10.1021/es703227g.

Amos, B. A., E. J. Suchomel, K. D. Pennell, and F. E. Löffler. 2008. Microbial activity and distribution during enhanced contaminant dissolution from a NAPL source zone. Water Research 42:2963-2974. | doi: 10.1016/j.watres.2008.03.015.

Thomas, S. H., R. D. Wagner, A. K. Arakaki, J. Skolnick, J. R. Kirby, L. J. Shimkets, R. A. Sanford, and F. E. Löffler. 2008. The mosaic genome of Anaeromyxobacter dehalogenans strain 2CP-C suggests an aerobic common ancestor to the delta-proteobacteria. PLoS ONE 3(5): e2103. | doi:10.1371/journal.pone.0002103.

Bradley, P. M., F. H. Chapelle, and F. E. Löffler. 2008. Anoxic mineralization: environmental reality or laboratory artifact? Ground Water Monitoring and Remediation. 28:47-49. | doi.org/10.1111/j.1745-6592.2007.00186.x.

Amos, B. K., Y. Sung, K. E. Fletcher, T. J. Gentry, W.-M. Wu, C. S. Criddle, J. Zhou, and F. E. Löffler. 2007. Detection and quantification of Geobacter lovleyi strain SZ: implications for bioremediation at tetrachloroethene- (PCE-) and uranium-impacted sites. Appl. Environ. Microbiol. 73:6898-6904. | doi: 10.1128/AEM.01218-07.

2007

Sanford, R. A., Q. Wu, Q., Y. Sung, S. H. Thomas, B. K. Amos, E. K. Prince, and F. E. Löffler. 2007. Hexavalent uranium supports growth of Anaeromyxobacter dehalogenans and Geobacter spp. with lower than predicted biomass yields. Environ. Microbiol. 9:2885-2893.

Bedard, D. L., K. M. Ritalahti and F. E. Löffler. 2007. Dehalococcoides in a sediment-free, mixed culture metabolically dechlorinate the commercial polychlorinated biphenyl mixture Aroclor 1260. Appl. Environ. Microbiol. 73:2513-2521. | doi: 10.1128/AEM.02909-06.

Daprato, R. C., F. E. Löffler, and J. B. Hughes. 2007. Comparative analysis of three tetrachloroethene to ethene halorespiring consortia suggests functional redundancy. Environ. Sci. Technol. 41:2261-2269. doi: 10.1021/es061544p.

Amos B. K., R. C. Daprato, J. B. Hughes, K. D. Pennell, and F. E. Löffler. 2007. Effect of the nonionic surfactant Tween 80 on microbial reductive dechlorination of chloroethenes. Environ. Sci. Technol. 41:1710-1716. | doi: 10.1289/ehp.6932.

Amos, B. K., J. A. Christ, L. M. Abriola, K. D. Pennell, and F. E Löffler. 2007. Experimental evaluation and mathematical modeling of microbially-enhanced tetrachloroethene (PCE) dissolution. Environ. Sci. Technol. 41:963-970. doi 10.1021/es061438n.

Krajmalnik-Brown, Y. Sung, R., K. M. Ritalahti, F. Michael Saunders, and F. E. Löffler. 2007. Environmental distribution of the trichloroethene reductive dehalogenase gene (tceA ) suggests lateral gene transfer among Dehalococcoides . FEMS Microbiol. Ecol. 59:206-214.

2006

Löffler, F. E. 2006. Bakterieller Abbau von Vinylchlorid. LaborPraxis, Juli/August 2006.

Löffler, F. E., and E. A. Edwards. 2006. Harnessing microbial activities for environmental cleanup. Curr. Opin. Biotechnol. 17:274-284.

Okutman-Tas, D., I. N. Thomson, F. E. Löffler, and S. G. Pavlostathis. 2006. Kinetics of the microbial reductive dechlorination of pentachloroaniline. Environ. Sci. Technol. 40:4467-4472.

Wu, Q., R. A. Sanford, and F. E. Löffler. 2006. Uranium (VI) reduction by Anaeromyxobacter dehalogenans strain 2CP-C. Appl. Environ. Microbiol. 72:3608-3614.

Rittmann, B. E, M. Hauser, F. E. Löffler, N. G. Love, G. Muyzer, S. Okabe, D. B. Oerther, J. Peccia, L. Raskin, and M. Wagner. 2006. A vista for microbial ecology and environmental biotechnology. Environ. Sci. Technol. 40:1096-1103.

Sung, Y, K. M. Ritalahti, R. P. Apkarian, and F. E. Löffler. 2006. Quantitative PCR confirms purity of strain GT, a novel trichloroethene (TCE)-to-ethene-respiring Dehalococcoides isolate. Appl. Environ. Microbiol. 72:1980-1987.

Ritalahti, K. M., B. K. Amos, Y. Sung, Q. Wu, S. S. Koenigsberg, and F. E. Löffler. 2006. Quantitative PCR targeting 16S rRNA and reductive dehalogenase genes simultaneously monitors multiple Dehalococcoides strains. Appl. Environ. Microbiol. 72:2765-2774. doi: 10.1128/AEM.72.4.2765-2774.2006.

Sung, Y., K. E. Fletcher, K. M. Ritalahti, R. P. Apkarian, N. Ramos-Hernández, R. A. Sanford, N. M. Mesbah, and F. E. Löffler. 2006. Geobacter lovleyi strain SZ sp. nov., a novel metal-reducing and tetrachloroethene (PCE)-dechlorinating bacterium. Appl. Environ. Microbiol. 72:2775-2782.

Tront, J. M., B. K. Amos, F. E. Löffler, and F. M. Saunders. 2006. Activity of Desulfitobacterium sp. strain Viet1 demonstrates bioavailability of 2,4-dichlorophenol previously sequestered by the aquatic plant Lemna minor. Environ. Sci. Technol. 40:529-535.

2005

Löffler, F. E., R. A. Sanford, and K. M. Ritalahti. 2005. Enrichment, cultivation, and detection of reductively dechlorinating bacteria. Methods Enzymol. Vol. 397:77-111.

Löffler, F. E., and R. A. Sanford. 2005. Analysis of trace hydrogen metabolism. Methods Enzymol. Vol. 397:222-237.

Waller, A. S., R. Krajmalnik-Brown, F. E. Löffler, and E. A. Edwards. 2005. Multiple reductive-dehalogenase-homologous genes are simultaneously transcribed during dechlorination by Dehalococcoides -containing cultures. Appl. Environ. Microbiol. 71:8257-8264.

White, D. C., R. Geyer, A. D. Peacock, D. B. Hedrick, S. S. Koenigsberg, Y. Sung, J. He, and F. E. Löffler. 2005. Phospholipid furan fatty acids and ubiquinone-8: Possible free radical protective lipid biomarkers in Dehalococcoides . Appl. Environ. Microbiol. 71:8426-8433.

He, J., Y. Sung, R. Krajmalnik Brown, K. M. Ritalahti, and F. E. Löffler. 2005. Isolation and characterization of Dehalococcoides sp. strain FL2, a trichloroethene (TCE)- and 1,2-dichloroethene-respiring anaerobe. Environ. Microbiol. 7:1442-1450.

Ritalahti, K. M., F. E. Löffler, E. R. Rasch, and S. S. Koenigsberg. 2005. Bioaugmentation for chlorinated solvent detoxification: Bioaugmentation and molecular diagnostics in the bioremediation of chlorinated ethene-contaminated sites. Industrial Biotechnology, 1:114-118.

Christ, J. A., C. A. Ramsburg, L. M. Abriola, K. D. Pennell, and F. E. Löffler. 2005. Coupling aggressive mass removal with microbial reductive dechlorination for remediation of DNAPL source zones – a review and assessment. Environ. Health Perspec. 113:465-477.

2004

Ramsburg, C. A., L. M. Abriola, K. D. Pennell, F. E. Löffler, M. Gamache, B. K. Amos, and E. A. Petrovskis. 2004. Stimulated microbial reductive dechlorination following surfactant treatment at the Bachman Road Site. Environ. Sci. Technol. 38:5902-5914.

Krajmalnik-Brown, R., T. Hölscher, I. N. Thomson, F. M. Saunders, K. M. Ritalahti, and F. E. Löffler. 2004. Genetic identification of a putative vinyl chloride reductase in Dehalococcoides sp. strain BAV1. Appl. Environ. Microbiol. 70:6347-6351.

Hölscher, T., R. Krajmalnik-Brown, K. M. Ritalahti, F. von Wintzingerode, H. Görisch, F. E. Löffler, and L. Adrian. 2004. Multiple non-identical putative reductive dehalogenase genes are common in Dehalococcoides . Appl. Environ. Microbiol. 70:5290-5297.

Griffin, B. M., J. M. Tiedje, and F. E. Löffler. 2004. Anaerobic microbial reductive dechlorination of tetrachloroethene (PCE) to predominately trans-1,2-dichloroethene. Environ. Sci. Technol. 38:4300-4303.

Ritalahti, K. M., and F. E. Löffler. 2004. Populations implicated in the anaerobic reductive dechlorination of 1,2-dichloropropane in highly enriched bacterial communities. Appl. Environ. Microbiol. 70:4088-4095.

Singh, H., F. E. Löffler, and B. Z. Fathepure. 2004. Aerobic biodegradation of vinyl chloride by a highly enriched mixed culture. Biodegradation 15:197-204.

2003

He, J., K. M. Ritalahti, K.-L. Yang, S. S. Koenigsberg, and F. E. Löffler. 2003. Detoxification of vinyl chloride to ethene coupled to growth of an anaerobic bacterium. Nature 424:62-65.

Major, D., E. Edwards, P. McCarty, J. Gossett, E. Hendrickson, F. Löffler, S. Zinder, D. Ellis, J. Vidumsky, M. Harkness, G. Klecka, and E. Cox. 2003. Discussion of environment vs. bacteria or let’s play, ‘name that bacteria’. Ground Water Monitoring &Remediation, 23:32-38.

Sung, Y, K. M. Ritalahti, R. A. Sanford, J. W. Urbance, S. J. Flynn, J. M. Tiedje, and F. E. Löffler. 2003. Characterization of two tetrachloroethene (PCE)-reducing, acetate-oxidizing anaerobic bacteria, and their description as Desulfuromonas michiganensis sp. nov. Appl. Environ. Microbiol. 69:2964-2974.

He, J., K. M. Ritalahti, M. R. Aiello, and F. E. Löffler. 2003. Complete detoxification of vinyl chloride by an anaerobic enrichment culture and identification of the reductively dechlorinating population as a Dehalococcoides species. Appl. Environ. Microbiol. 69:996-1003.

Lendvay, J. M., F. E. Löffler, M. Dollhopf, M. R. Aiello, G. Daniels, B. Z. Fathepure, M. Gebhard, R. Heine, R. Helton, J. Shi, R. Krajmalnik-Brown, C. L. Major, Jr., M. J. Barcelona, E. Petrovskis, R. Hickey, J. M. Tiedje, and P. Adriaens. 2003. Bioreactive barriers: a comparison of bioaugmentation and biostimulation for chlorinated solvent remediation. Environ. Sci. Technol. 37:1422-1431.

Gee, W. A., K. M. Ritalahti, W. D. Hunt, and F. E. Löffler. 2003. QCM viscometer for bioremediation and microbial activity monitoring. IEEE Sensors Journal, 3:304-309.

McKinsey, P. C., R. L. Brigmon, M. A. Heitkamp, J. Rossabi, and F. E. Löffler. 2003. Bioremediation of trichloroethylene-contaminated sediments augmented with a Dehalococcoides consortium. Battelle Press, Columbus, OH.

Löffler, F. E., J. R. Cole, K. M. Ritalahti, and J. M. Tiedje. 2003. Diversity of dechlorinating bacteria, p. 53-87. In M. M. Häggblom and I. D. Bossert (eds.), Dehalogenation: microbial processes and environmental applications. Kluwer Academic, New York.

1991-2002

He, J. Y. Sung, M. E. Dollhopf, B. Z. Fathepure, J. M. Tiedje, and F. E. Löffler. 2002. Acetate versus hydrogen as direct electron donors to stimulate the microbial reductive dechlorination process at chloroethene-contaminated sites. Environ. Sci. Technol. 36:3945-3952.

Lendvay, J.M., M.J. Barcelona, G. Daniels, M. Dollhopf, B.Z. Fathepure, M. Gebhard, R. Heine, R. Hickey, F.E. Löffler, C.L. Major, E.A. Petrovskis, J. Shi, J. Tiedje, and P. Adriaens. 2002. Plume control using bioaugmentation with halorespiring microorganisms. Groundwater Quality: Natural and Enhanced Restoration of Groundwater Pollution Book Series: IAHS Publication, Issue: 275:325-332.

Tesoriero, A. J., F. E. Löffler, and H. Liebscher. 2001. The fate and origin of fumigant-related compounds in an unconfined shallow aquifer. Environ. Sci. Technol. 35:455-461.

Löffler, F. E. and K. M. Ritalahti. 2001. 16S rDNA-based tools identify Dehalococcoides species in many reductively dechlorinating enrichment cultures, p. 53-68. In M. A. Kornmüller (ed.), Anaerobic dehalogenation. SFB 193 Biological Waste Water Remediation, Technical University Berlin, Germany.

Lendvay, J. M., M. J. Barcelona, B. Z. Fathepure, R. Hickey, F. E. Löffler, E. Petrovskis, J. M. Tiedje, and P. Adriaens. 2001. Preventing contaminant discharge to surface waters: plume control with bioaugmentation, p. 19-26. In Bioaugmentation, Biobarriers, and Biogeochemistry, A. Leeson and B. C. Alleman, P. J. Alvarez, and V. S. Magar (eds.), Battelle Press, Columbus, OH.

Löffler, F. E., Q. Sun, J. Li, and J. M. Tiedje. 2000. 16S rRNA Gene-based detection of tetrachloroethene (PCE)-dechlorinating Desulfuromonas and Dehalococcoides species. Appl. Environ. Microbiol. 66:1369-1374.

Flynn, S. J., Löffler, F. E., and J. M. Tiedje. 2000. Microbial community changes associated with a shift from reductive dechlorination of PCE to reductive dechlorination of cis-DCE and VC. Environ. Sci. Technol. 34:1056-1061.

Löffler, F. E., J. M. Tiedje, and R. A. Sanford. 1999. The fraction of electrons consumed in electron acceptor reduction (f_e ) and hydrogen thresholds as indicators of halorespiratory physiology. Appl. Environ. Microbiol. 65:4049-4056.

Brennan, R. A., A. R. Swanson, F. E. Löffler, and R. A. Sanford. 1999. Chlorinated solvent bioremediation: a novel approach to measuring bacterial kinetics, p. 21-26. In Engineering Approaches for In Situ Bioremediation of Chlorinated Solvent Contamination, A. Leeson and B. C. Alleman (eds.), Battelle Press, Columbus, OH.

Wischnak, C., F. E. Löffler, J. Li, J. W. Urbance, and R. Müller. 1998. Isolation and characterization of a Pseudomonas species that degrades medium length α,ω-dichloroalkanes. Appl. Environ. Microbiol. 64:3507-3511.

Löffler, F. E., J. E. Champine, K. M. Ritalahti, S. J. Sprague, and J. M. Tiedje. 1997. Complete reductive dechlorination of 1,2-dichloropropane by anaerobic bacteria. Appl. Environ. Microbiol. 63:2870-2875.

Löffler, F. E., K. M. Ritalahti, and J. M. Tiedje. 1997. Dechlorination of chloroethenes is inhibited by 2-bromoethanesulfonate in the absence of methanogens. Appl. Environ. Microbiol. 63:4982-4985.

Löffler, F. E., R. A. Sanford, and J. M. Tiedje. 1996. Initial characterization of a reductive dehalo-genase from Desulfitobacterium chlororespirans Co23. Appl. Environ. Microbiol. 62:3809-3813.

Sanford, R. A., J. R. Cole, F. E. Löffler, and J. M. Tiedje. 1996. Characterization of Desulfitobacterium chlororespirans sp. nov., which grows by coupling the oxidation of lactate to the reductive dechlorination of 3-chloro-4-hydroxybenzoate. Appl. Environ. Microbiol. 62:3800-3808.

Löffler, F., F. Lingens, and R. Müller. 1995. Dehalogenation of 4-chlorobenzoate: Characterization of 4-chlorobenzoyl-coenzyme A dehalogenase from Pseudomonas sp. CBS3. Biodegradation 6:203-212.

Löffler, F., R. Müller, and F. Lingens. 1992. Purification and characterization of 4-halobenzoate-coenzyme A ligase from Pseudomonas sp. CBS3. Biol. Chem. Hoppe-Seyler 373:1001-1007.

Löffler, F., and R. Müller. 1991. Identification of 4-chlorobenzoyl-coenzyme A as intermediate in the dehalogenation catalyzed by 4-chlorobenzoate dehalogenase from Pseudomonas sp. CBS3. FEBS Lett. 290:224-226.

Löffler, F., R. Müller, and F. Lingens. 1991. Dehalogenation of 4-chlorobenzoate by 4-chlorobenzoate dehalogenase from Pseudomonas sp. CBS3: an ATP/coenzyme A dependent reaction. Biochem. Biophys. Res. Commun. 176:1106-1111.

Elsner, A., F. Löffler, K. Miyashita, R. Müller, and F. Lingens. 1991. Resolution of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS3 into three components. Appl. Environ. Microbiol. 57:324-326.